Research Markets

Development of Reductive C-S Coupling for Preparing S-Aryl/alkyl Containing Peptides.

Oct 30, 2026 Source ↗

Key Insights

Herein, we report a robust reductive coupling of cysteine thiosulfonate derivatives with aryl/alkyl halides, enabling chemoselective modification of peptides.
Using zinc as the reducing agent, it provides a divergent platform for construction of Csp3/Csp2─S bonds, featuring base-free reaction condit.

Cite this synthesis DOI: 10.1021/acs.joc.6c02145 ↗

Show formatted citation

@misc{ acaciamarkets-research-development-of-reductive-c-s-coupling-for-preparing-s-aryl-a,
  title = { Development of Reductive C-S Coupling for Preparing S-Aryl/alkyl Containing Peptides. },
  author = { J Wang, Q Fan, C Wang et al. },
  year = { 2026 },
  doi = { 10.1021/acs.joc.6c02145 },
  url = { https://pubmed.ncbi.nlm.nih.gov/42895049/ },
  note = {Summarized and classified by AcaciaFund}
}

TY  - GEN
TI  - Development of Reductive C-S Coupling for Preparing S-Aryl/alkyl Containing Peptides.
AU  - J Wang, Q Fan, C Wang et al.
PY  - 2026
DO  - 10.1021/acs.joc.6c02145
UR  - https://pubmed.ncbi.nlm.nih.gov/42895049/
ER  -

Edit on GitHub — registry.json

Overview

Herein, we report a robust reductive coupling of cysteine thiosulfonate derivatives with aryl/alkyl halides, enabling chemoselective modification of peptides. Using zinc as the reducing agent, it provides a divergent platform for construction of Csp3/Csp2─S bonds, featuring base-free reaction conditions, operational simplicity, and broad substrate compatibility.

Key Topics

Market Microstructure: A theme covered by this item within the markets context.
Quantitative Modeling: A theme covered by this item within the markets context.

Why It Matters

This item adds to the markets knowledge base. Practitioners can use it to stay current on Development of Reductive C-S Coupling for Preparing S-Aryl/alkyl Containing Peptides, but should validate its claims against primary sources and more recent work before relying on it in production decisions.

Key Takeaways

Understand how Development of Reductive C-S Coupling for Preparing S-Aryl/alkyl Containing Peptides relates to markets workflows and controls.
Assess evidence quality and freshness before acting on the findings.
Use the tagged topics to connect this item to related content in the library.

Article Metadata

Evergreen Synthesized

quantitative-modeling market-microstructure agentic-systems derivatives

Market Microstructure

SQI 0.700