Research Data Engineering

Crosstalk between mitophagy and metabolism in cancer: Mechanisms and therapeutic opportunities.

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Key Insights

  • Mitophagy is a highly selective autophagic process that eliminates dysfunctional mitochondria to enforce stringent cellular quality control, acting as a context-dependent modulator of stress adaptation in cancer cells.
  • Concurrently, to thrive in hostile microenvironments, cancer cells undergo extens.
Cite this synthesis DOI: 10.1016/j.freeradbiomed.2026.08.004 ↗
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@misc{ acaciadata-research-crosstalk-between-mitophagy-and-metabolism-in-cancer-mechani,
  title = { Crosstalk between mitophagy and metabolism in cancer: Mechanisms and therapeutic opportunities. },
  author = { J Cheng, T Xiao, Z Tang et al. },
  year = { 2026 },
  doi = { 10.1016/j.freeradbiomed.2026.08.004 },
  url = { https://pubmed.ncbi.nlm.nih.gov/42546808/ },
  note = {Summarized and classified by AcaciaFund}
}
TY  - GEN
TI  - Crosstalk between mitophagy and metabolism in cancer: Mechanisms and therapeutic opportunities.
AU  - J Cheng, T Xiao, Z Tang et al.
PY  - 2026
DO  - 10.1016/j.freeradbiomed.2026.08.004
UR  - https://pubmed.ncbi.nlm.nih.gov/42546808/
ER  -

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Overview

Mitophagy is a highly selective autophagic process that eliminates dysfunctional mitochondria to enforce stringent cellular quality control, acting as a context-dependent modulator of stress adaptation in cancer cells. Concurrently, to thrive in hostile microenvironments, cancer cells undergo extensive metabolic reprogramming to fulfill the immense bioenergetic and anabolic demands of rapid proliferation. Rather than operating independently, mitophagy and metabolism are intrinsically coupled to

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This item adds to the data engineering knowledge base. Practitioners can use it to stay current on Crosstalk between mitophagy and metabolism in cancer: Mechanisms and therapeutic opportunities, but should validate its claims against primary sources and more recent work before relying on it in production decisions.

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