Monitoring Mitochondrial Function With High-Resolution Respirometry During Ex-Situ Heart Perfusion.
Key Insights
- Due to the high adenosine-triphosphate (ATP) consumption of the myocardial tissue, cardiac function is dependent on efficient mitochondrial respiration.
- Ischemia and reperfusion injury (I/R) has a severe impact on the function of the mitochondrial respiratory system.
- Ex-situ heart perfusion (ESHP) c.
Show formatted citation
@misc{ acaciadata-research-monitoring-mitochondrial-function-with-high-resolution-respi,
title = { Monitoring Mitochondrial Function With High-Resolution Respirometry During Ex-Situ Heart Perfusion. },
author = { L Stastny, J Hofmann, AT Meszaros et al. },
year = { 2026 },
doi = { 10.1111/aor.70213 },
url = { https://pubmed.ncbi.nlm.nih.gov/42723391/ },
note = {Summarized and classified by AcaciaFund}
}
TY - GEN TI - Monitoring Mitochondrial Function With High-Resolution Respirometry During Ex-Situ Heart Perfusion. AU - L Stastny, J Hofmann, AT Meszaros et al. PY - 2026 DO - 10.1111/aor.70213 UR - https://pubmed.ncbi.nlm.nih.gov/42723391/ ER -
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Overview
Due to the high adenosine-triphosphate (ATP) consumption of the myocardial tissue, cardiac function is dependent on efficient mitochondrial respiration. Ischemia and reperfusion injury (I/R) has a severe impact on the function of the mitochondrial respiratory system. Ex-situ heart perfusion (ESHP) can minimize I/R injury.
We investigated mitochondrial respiration using high-resolution respirometry (HRR) in a porcine model during ESHP.
Key Topics
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